Utilization of cell proliferation markers to diagnose cystic jaw pathologies

Markers of cell proliferation are widely used as diagnostic and prognostic tools. Coincident estimation these markers increases the precise evaluation proliferative status different tissues can also be helpful in determining progression, aggressiveness prognosis lesions. The current study investigated expression PCNA MCM3 40 formalin fixed paraffin embedded tissue blocks odontogenic keratocyst (OKC) unicystic ameloblastoma (UA) cases using immunohistochemistry method. Markers` based on intensity, percentage positively stained cells localization reaction through cyst lining epithelium was separately analyzed for each marker Chi square test, results which were significant two (P < 0.05). Both revealed statistically differences between OKC UA regarding positivity score epithelium. Mural histologic variant significantly than luminal intraluminal variants. correlation coefficient found to 0.86.